Jadwal pertandingan liga spanyol terlengkap. Hanya di DemenBola.com:
| 11/09/2021 | ||
| Villarreal | 23:30 | Alaves |
| 12/09/2021 | ||
| Sevilla | 02:00 | Barcelona |
| 17/10/2021 | ||
| Granada | 07:00 | Atlético de Madrid |
| Real Madrid | 07:00 | Athletic Bilbao |
| 23/10/2021 | ||
| Valencia | 19:00 | Mallorca |
| Cadiz | 21:15 | Alaves |
| Elche | 23:30 | Espanyol |
| 24/10/2021 | ||
| Athletic Bilbao | 02:00 | Villarreal |
| Sevilla | 19:00 | Levante |
| Barcelona | 21:15 | Real Madrid |
| Real Betis | 23:30 | Rayo Vallecano |
| 25/10/2021 | ||
| Atlético de Madrid | 02:00 | Real Sociedad |
| 26/10/2021 | ||
| Getafe | 02:00 | Celta Vigo |
| 27/10/2021 | ||
| Alaves | 00:00 | Elche |
| Espanyol | 02:00 | Athletic Bilbao |
| Villarreal | 02:30 | Cadiz |
| 28/10/2021 | ||
| Mallorca | 00:00 | Sevilla |
| Rayo Vallecano | 00:00 | Barcelona |
| Real Betis | 01:00 | Valencia |
| Real Madrid | 02:30 | Osasuna |
Hasil pertandingan liga spanyol terlengkap. Hanya di DemenBola.com:
| 23/10/2021 | ||
| Osasuna | 1 - 1 | Granada |
| 19/10/2021 | ||
| Espanyol | 2 - 0 | Cadiz |
| Alaves | 0 - 1 | Real Betis |
| 18/10/2021 | ||
| Barcelona | 3 - 1 | Valencia |
| 17/10/2021 | ||
| Villarreal | 1 - 2 | Osasuna |
| Celta Vigo | 0 - 1 | Sevilla |
| Rayo Vallecano | 2 - 1 | Elche |
| Real Sociedad | 1 - 0 | Mallorca |
| 16/10/2021 | ||
| Levante | 0 - 0 | Getafe |
| 04/10/2021 | ||
| Granada | 1 - 0 | Sevilla |
| 03/10/2021 | ||
| Villarreal | 2 - 0 | Real Betis |
| Getafe | 1 - 1 | Real Sociedad |
| Espanyol | 2 - 1 | Real Madrid |
| Elche | 1 - 0 | Celta Vigo |
| Atlético de Madrid | 2 - 0 | Barcelona |
| 02/10/2021 | ||
| Cadiz | 0 - 0 | Valencia |
| Mallorca | 1 - 0 | Levante |
| Osasuna | 1 - 0 | Rayo Vallecano |
| Athletic Bilbao | 1 - 0 | Alaves |
| 28/09/2021 | ||
| Celta Vigo | 1 - 0 | Granada |
